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Literature summary for 3.1.4.39 extracted from
- Synthesis and evaluation of fluorogenic substrates for phospholipase D and phospholipase C (2006), Org. Lett., 8, 2575-2578.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | fluorogenic substrates, potential in screening for inhibitors and for monitoring spatiotemporal changes in activity in cells | Bacillus cereus |
| analysis | fluorogenic substrates, potential in screening for inhibitors and for monitoring spatiotemporal changes in activity in cells | Clostridium perfringens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lysophosphatidylcholine + H2O | Bacillus cereus | - |
lysophosphatidic acid + choline | - |
? |  |
| lysophosphatidylcholine + H2O | Clostridium perfringens | - |
lysophosphatidic acid + choline | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus cereus | - |
- |
- |
| Clostridium perfringens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lysoDDPB + H2O | synthesized by an enzyme-assisted strategy. Lysophosphatidylcholine analogue that contains a fluorescence quencher at each acyl chain terminus and a fluorophore appended to the phospholipid headgroup through a choline-mimetic linker | Bacillus cereus | ? | - |
? | |
| lysophosphatidylcholine + H2O | - |
Bacillus cereus | lysophosphatidic acid + choline | - |
? | |
| lysophosphatidylcholine + H2O | - |
Clostridium perfringens | lysophosphatidic acid + choline | - |
? | |
| [(11R)-1-(4-[(Z)-[4-(dimethylamino)phenyl]diazenyl]phenyl)-N-[3-[(5-[5-[(3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)methyl]-1H-pyrrol-2-yl-kappaN]pentanoyl)amino]propyl]-11,14-dihydroxy-N,N-dimethyl-1,8-dioxo-9,13,15-trioxa-2-aza-14-phosphaheptadecan-17-aminiumato 14-oxide](difluoro)boron(1+) + H2O | synthesized by an enzyme-assisted strategy. lysophosphatidylcholine analogue that contains a fluorescence quencher at each acyl chain terminus and a fluorophore append to the phospholipid headgroup through a choline-mimetic linker | Clostridium perfringens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| lysophospholipase D | - |
Bacillus cereus |
| lysophospholipase D | - |
Clostridium perfringens |
| lysoPLD | - |
Bacillus cereus |
| lysoPLD | - |
Clostridium perfringens |
| lysoPLD autotaxin | nucleotide pyrophosphatase/phosphodiesterase, catalyzes hydrolysis via an active site threonine | Bacillus cereus |
| lysoPLD autotaxin | nucleotide pyrophosphatase/phosphodiesterase, catalyzes hydrolysis via an active site threonine | Clostridium perfringens |
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